MARINE COLLAGEN NATICOL® / HYALURONIC ACID (POWDER) - 300G

The benefits of marine collagen for the skin are vast and significant, making this supplement a preferred choice for those wishing to improve the quality and appearance of their epidermis.

Thanks to its unique composition, rich in essential proteins and amino acids, marine collagen plays a key role in maintaining skin hydration, firmness and elasticity.

Firstly, one of the major advantages of marine collagen lies in its ability to improve skin hydration. By strengthening the skin barrier, it helps retain moisture, which is essential for supple and hydrated skin. Good hydration is the foundation of healthy skin, helping to prevent dryness and maintain a visibly fresh and radiant appearance.

In addition, marine collagen contributes to increasing the firmness and elasticity of the skin. With age, the natural production of collagen decreases, leading to a loss of elasticity and firmness, which can result in the appearance of wrinkles and fine lines. Marine collagen supplementation can help compensate for this loss, by providing the necessary elements for the skin to maintain its structure and resistance.

Furthermore, marine collagen is effective in reducing the appearance of visible signs of aging, such as wrinkles and fine lines. By supporting the structure of the skin, it helps smooth and firm the epidermis, which can lead to a visible reduction of age-related imperfections.

The high bioavailability of marine collagen is another major asset, as it ensures optimal assimilation by the body. This means that the nutrients contained in marine collagen are easily absorbed and used by the skin, thereby maximizing the benefits of supplementation.

In conclusion, marine collagen offers a multitude of benefits for the skin, contributing to its hydration, firmness and elasticity, while fighting the signs of aging. Its ability to be effectively assimilated by the body ensures a targeted and beneficial action, making it a valuable ally for maintaining healthy and radiant skin.

Our marine collagen powder is a valuable ally in the fight against skin aging, particularly by helping to maintain its elasticity. This substance, essential for skin beauty, works by stimulating collagen synthesis, a key protein for preserving skin firmness and suppleness. By strengthening the dermis, it effectively combats deep wrinkles and slows down the signs of aging, while preventing skin sagging often associated with age.

In addition, marine collagen helps regenerate the epidermis, thereby promoting the formation of natural collagen essential for beautiful, hydrated and firm skin. Its firming and hydrating action contributes to slowing down premature aging and preventing premature sagging, while increasing the level of collagen in the skin. Effective on all skin types, marine collagen is also beneficial for mature skin, which naturally undergoes a decrease in collagen production with age.

Regular use of marine collagen cures can therefore play a key role in keeping skin beautiful and youthful longer. It acts as a powerful anti-wrinkle treatment, while helping to firm and hydrate the epidermis. This preventive and curative approach makes it an ideal solution for people looking to stimulate collagen production and fight the skin effects of aging, thereby ensuring mature skin that is radiant with health and vitality.

Marine collagen, particularly when consumed in powder form, is a food supplement of choice for individuals dealing with conditions such as osteoarthritis or various joint problems.

This form of collagen is recognized for its beneficial properties on the health of cartilage and connective tissues.

The interest of marine collagen for people suffering from osteoarthritis or joint problems is explained by its composition rich in specific amino acids, such as glycine and proline. These amino acids play a crucial role in the regeneration of connective tissues, thereby helping to improve joint suppleness and mobility.

Marine collagen powder supplementation can therefore help relieve symptoms associated with osteoarthritis, such as joint pain and stiffness, by promoting the repair and maintenance of damaged cartilage.

In addition, marine collagen has the advantage of being easily assimilated by the body, compared to other sources of collagen. This high bioavailability ensures optimal effectiveness of the supplement, allowing essential nutrients to reach directly the tissues requiring repair and support.

In summary, marine collagen powder proves to be a valuable ally for people suffering from osteoarthritis or joint problems, thanks to its ability to promote the regeneration of cartilage and connective tissues, thereby improving joint suppleness and function.

Exposure of marine collagen powder to moderate heat, such as that of a hot drink, generally does not significantly alter its peptides.

Our collagen powder is designed to withstand high temperatures without losing its beneficial properties.

Exposure to the moderate heat of a hot drink generally does not significantly alter its peptides.

The molecular weight of collagen is crucial because it directly influences its assimilation by the body.

A lower molecular weight, typical of hydrolyzed collagen, facilitates the absorption and use of collagen peptides by the body.

This allows for better integration into target tissues, such as skin, bones and joints, thereby improving the effectiveness of collagen for cellular regeneration, skin health and the support of connective structures.

Hyaluronic acid and vitamin C play complementary and essential roles when combined with marine collagen in a formula designed to improve the health and appearance of the skin.

Each of these components brings its own benefits, which, in synergy, optimize the effects of marine collagen.

• Hyaluronic Acid: Hyaluronic acid is a molecule naturally present in the human body, especially in the skin, where it plays a crucial role in hydration and the maintenance of skin structure. Its ability to retain up to 1000 times its weight in water makes it a highly hydrating component, essential for keeping the skin supple, hydrated and plump. In combination with marine collagen, hyaluronic acid helps maximize skin hydration, reduce the appearance of fine lines and promote a smoother and firmer skin texture.
• Vitamin C: Vitamin C, or ascorbic acid, is a powerful antioxidant that helps protect the skin from damage caused by free radicals, such as those resulting from UV exposure, pollution and other harmful environmental factors. Vitamin C also plays a vital role in collagen synthesis, helping to stimulate the natural production of collagen by the body. It promotes the repair and renewal of skin tissues, thereby contributing to improving the elasticity and firmness of the skin. In addition, vitamin C can help brighten the skin tone and reduce the appearance of pigmentation spots, offering a more even and radiant complexion.

In summary, the combination of hyaluronic acid and vitamin C with marine collagen in a formula dedicated to skin care delivers a triple action: deep hydration, antioxidant protection, and support for collagen production.

This synergy significantly improves the quality of the skin in terms of hydration, firmness, elasticity and radiance, thus offering a complete solution to fight the signs of skin aging.

Yes, it is recommended to take collagen daily for optimal effectiveness. There is no contraindication to consuming marine collagen continuously at the recommended doses, making it a safe option for long-term use.

Regular intake over a period of 2 to 3 months, repeated 2 to 3 times a year, helps maintain the beneficial effects on the appearance of wrinkles, wrinkles and fine lines, and promotes cellular renewal.

This routine supports skin health by reducing the signs of aging and improving skin texture and elasticity. In addition, collagen improves joint comfort, supports performance in sports nutrition, and optimizes intestinal comfort.

Yes, numerous scientific and clinical studies support the efficacy of Naticol® collagen.

These studies, carried out in collaboration with research institutes and clinics such as INSERM, Paul Sabatier University and the Nice University Hospital Center, demonstrate benefits in the fields of nutricosmetics, joint comfort, healthy aging, sports nutrition and intestinal comfort. The types of studies conducted include consumer panels, in vitro, in vivo, pre-clinical and clinical studies.

Here are some studies and their results:

1. Professional summary of the study on Naticol® and collagen synthesis

Background

Collagen is the most abundant protein in the human body and plays a key role in mechanical functions, particularly in connective tissues. It provides strength, support, shape and elasticity to tissues. However, the collagen matrix is often the target of destructive processes, which underlines the importance of its regeneration.

Naticol®

Naticol® is a product made of marine collagen peptides. In vitro studies were carried out to evaluate its impact on collagen synthesis and its anti-inflammatory effects.

Methodology

Human monocyte-derived macrophages (h-MDMs) and keratinocytes (HaCat) were grown in a co-culture system. These cells were stimulated with LPS (lipopolysaccharide) to induce a pro-inflammatory phenotype, then treated with Naticol® (1 mg/ml). The expression levels of several markers were measured:

• Collagen Synthase 3 (enzyme involved in collagen production)
• MMP13 (metallopeptidase involved in extracellular matrix degradation)
• TGF-β and IL-10 (anti-inflammatory and pro-resolving cytokines)

Key Results

Increased collagen synthesis

A significant increase in collagen synthesis was observed thanks to enhanced stimulation of collagen synthase 3.

Reduction in the expression of MMP13, the enzyme responsible for collagen degradation.

Anti-inflammatory effects

Naticol® promoted an increase in the expression of the anti-inflammatory cytokines TGF-β and IL-10, thereby reinforcing its soothing effect.

Conclusion

Naticol® offers notable competitive advantages, having demonstrated anti-inflammatory benefits and the ability to increase collagen synthesis. These effects make Naticol® a promising option for supporting the health of connective tissues and the regeneration of the extracellular matrix.

2. Professional summary of the study on Naticol® and beauty

Background

Today, consumers recognize the importance of nutrition for the beauty of skin, hair and nails. Collagen, in particular, has become a central ingredient in nutricosmetics thanks to its benefits for the skin and aging.

Naticol® and its beauty benefits

Naticol®, a marine collagen peptide, has demonstrated its efficacy in several clinical studies. These studies evaluated its impact on signs of skin aging, such as wrinkles, hydration, firmness and elasticity of the skin, as well as on the health of hair and nails.

Results of clinical studies

Double-blind, randomized, placebo-controlled clinical studies have shown that Naticol® (from 2.5 g/day) provides significant improvements on several beauty parameters after 8 to 12 weeks:

Wrinkle reduction

A reduction in crow's feet wrinkles and perioral wrinkles after 12 weeks of using Naticol®.

Improvement in skin hydration

Increase in skin hydration, enhancing the overall beauty of the skin.

Firmness and elasticity

Increase in skin elasticity and firmness thanks to a restructuring of the dermis.

Skin echogenicity (a measure of dermis density) increased, suggesting an improvement in dermis thickness.

Skin homogeneity

Skin homogeneity was improved, giving the skin a more even and luminous complexion.

Impact on hair and nails

Naticol® has also shown significant benefits on hair and nail health:

• Hair: 82% of volunteers reported shinier, less dry hair that is more resistant to breakage.
• Nails: 85% observed stronger nails and faster growth.

Conclusion

Naticol® stands out as a key ingredient for nutricosmetic products thanks to its proven effects on skin aging, hydration, firmness and the health of hair and nails. Its efficacy is supported by several clinical studies, thereby providing a natural solution to improve the beauty of the skin from within.

3. Professional summary of the study on Naticol® and joint health

Background

Osteoarthritis is a chronic degenerative disease that affects the joints, leading to pain, loss of mobility and a decrease in quality of life. Advanced age and obesity are the main risk factors for this disease, which is one of the leading causes of disability in elderly people.

Naticol® and joint health

Naticol® marine collagen peptides have been studied to evaluate their effectiveness in improving joint comfort, particularly in relieving the symptoms of knee osteoarthritis.

Methodology of the clinical study

A double-blind, randomized, placebo-controlled clinical study was carried out on 30 middle-aged subjects (61 years), over a duration of 8 and 12 weeks.

The criteria evaluated included:

• Pain and physical function scores according to the WOMAC scale (Western Ontario and McMaster Universities).
• Quality of life (QOL) through the score of limitations due to physical problems (SF-36V2).
• Physical performance with short battery tests (SPPB).

The study was conducted by Atlantia/Cork Hospital in Ireland and approved by a local ethics committee.

Key results

Pain reduction (WOMAC)

A significant decrease in pain scores was observed in the Naticol® group after 8 and 12 weeks of supplementation.

No notable improvement was observed in the placebo group.

Improvement in Physical Function (WOMAC)

The physical function score also improved significantly in subjects taking Naticol® at 12 weeks.

Physical performance (SPPB)

Subjects in the Naticol® group showed an improvement in physical performance, measured by the chair test, compared to the placebo group.

Quality of Life (SF-36V2)

An improvement in limitations due to physical problems was observed in the Naticol® group after 12 weeks, indicating a better quality of life.

Tolerance

Naticol® showed good general tolerance, with no significant adverse effects reported by volunteers.

Conclusion

Daily consumption of 10 g of Naticol® for 12 weeks demonstrated significant clinical benefits in relieving the symptoms of osteoarthritis, particularly pain and physical function. These results suggest that Naticol® can be a promising ingredient to support joint health, especially in people suffering from osteoarthritis.