SAFFRON (SAFR'INSIDE®)

Saffron (Crocus sativus L.) is the most precious spice in the world, nicknamed "red gold" since Antiquity. Revered by the pharaohs of Egypt, used by Cleopatra in her baths and prescribed by Persian physicians to soothe troubles of the mind, saffron has been used for over 3,000 years in traditional pharmacopoeias.

Beyond its ancient history, saffron is studied today for its role in mood support, stress management and emotional balance. It notably contains safranal and crocins, two families of bioactive compounds responsible for its effects on the nervous system and mental serenity.

Our saffron food supplement in capsules provides the patented French extract Safr'Inside®, at 30 mg per day, for easy integration into your daily routine.

Safr'Inside® is a patented saffron extract developed by the French laboratory Activ'Inside, based in Libourne, near Bordeaux. It is one of the few 100% French, clinically studied saffron extracts available on the market.

Its specificity lies in a proprietary encapsulation technology that preserves 10 times more safranal than standard extracts. Safranal is saffron's signature volatile compound, responsible for its action on emotional balance, but usually lost during classic extraction processes.

Safr'Inside® is standardised at 0.2% safranal measured by U-HPLC, guaranteeing consistent concentration and quality in every batch. This French innovation captures the active essence of saffron in a single capsule.

Saffron is a treasure of phytotherapy, containing several families of bioactive compounds studied by scientific research:

• Safranal: signature volatile compound, responsible for the aroma and the action on emotional balance
• Crocins and crocetin: carotenoids responsible for the red colour, with antioxidant action
• Picrocrocin: compound responsible for saffron's characteristic taste
• Flavonoids: natural antioxidant compounds
• Kaempferol: polyphenol studied for its protective properties

This wealth of bioactive compounds makes saffron one of the most versatile and precious medicinal plants in traditional pharmacopoeia.

Saffron can be taken at any time of day, according to your rhythm and preference. It is generally recommended to take it in the morning with a meal, with a large glass of water, to benefit from its effects on emotional balance throughout the day.

For occasional use, one capsule can be taken 30 minutes before a stressful event (public speaking, exam, tense situation), to benefit from the clinically demonstrated rapid calming action (Pouchieu et al., 2023 study).

A course of at least 1 to 3 months is recommended to fully benefit from its properties, as the effects on emotional balance build progressively with regular intake.

The effects of saffron occur on two complementary levels.

In the short term, a clinical study published in Nutrients in 2023 (Pouchieu et al.) demonstrated that a single 30 mg dose of Safr'Inside® significantly reduces perceived stress within 30 minutes of intake, during an acute stress test in the laboratory.

In the long term, the pivotal study published in Frontiers in Nutrition in 2020 (Jackson et al.) demonstrated a significant improvement in mood and emotional wellbeing in subjects supplemented with 30 mg/day of Safr'Inside® for 8 weeks. The benefits therefore build over time, with measurable results from 4 to 8 weeks of daily intake.

The saffron market is very uneven in quality. Many standard extracts lose a large part of their safranal, the key volatile compound, during traditional extraction processes (drying, grinding, exposure to heat or oxygen).

Safr'Inside® stands out for its proprietary encapsulation technology, which protects safranal from degradation and preserves 10 times more safranal than non-encapsulated extracts. In concrete terms, 30 mg of Safr'Inside® provides a significantly higher concentration of active compounds than an equivalent standard extract.

This French innovation is validated by several clinical studies published in international scientific journals (Frontiers in Nutrition, Nutrients, Food & Function), making it one of the best-documented saffron extracts in the world.

Yes, saffron combines particularly well with other food supplements with complementary properties.

Relevant combinations: Saffron + Magnesium+ for complete support of the nervous system and stress management; Saffron + Ashwagandha KSM-66® for a global adaptogenic, anti-stress approach; Saffron + B Vitamin Complex for complete energy and nervous support; Saffron + Optimal Sleep for those who wish to combine emotional balance and sleep quality.

It is advisable to introduce supplements one at a time over a few days to observe individual tolerance, and to seek advice from a healthcare professional if taking several supplements simultaneously.

No. Saffron is a traditional plant used for over 3,000 years, with no risk of habituation or dependence, unlike some anxiolytic or antidepressant medications.

At the recommended doses (30 mg/day), saffron is very well tolerated. Clinical studies published on Safr'Inside® reported no significant side effects compared to placebo.

It is nevertheless important not to exceed the recommended daily dose. At very high doses (above 1.5 g per day, which corresponds to 50 times the recommended dose), saffron can cause adverse effects. At the physiological dose of 30 mg/day, no risk is documented.

Saffron is generally well tolerated in capsule extract form, but certain precautions must be observed.

It is not recommended for pregnant and breastfeeding women, as saffron at high doses may have a uterotonic effect. Consumption is also not recommended for children under 12.

People taking antidepressant (particularly SSRI), anxiolytic or anticoagulant medication should seek their doctor's advice before use, as saffron may interact with these classes of medication.

For adults only. Do not exceed the recommended daily dose. A food supplement is not a substitute for a varied, balanced diet or a healthy lifestyle.

Yes. Our Nutrition•pro Saffron comes in plant-based capsules (HPMC) and contains no ingredients of animal origin. It is perfectly suitable for vegetarian and vegan diets.

Our formula is also gluten-free, lactose-free, GMO-free, with no added sugar, no colourings and no artificial preservatives. It is therefore suitable for people following specific diets or looking for food supplements with clean compositions.

Our saffron is made in France with the patented raw material Safr'Inside®, developed by Activ'Inside in Libourne, with particular attention to extract quality, traceability and transparency of composition.