MADE IN FRANCE
SHIITAKE
- Supports natural defences
- Rich in vitamins and minerals
- Complete nutritional mushroom
- Natural source of lentinan and β-glucans
FRANCE
NATURAL
EFFICIENCY
Description
The nutritional mushroom from the Japanese tradition
Cultivated for over a thousand years in Japan, Shiitake (Lentinula edodes) is the most widely consumed edible mushroom in the world. Its Japanese name means "mushroom (také) of the oak (shii)", referring to the tree on which it naturally grows in Asian forests. A pillar of Japanese, Chinese and Korean cuisine for centuries, it also holds a prominent place in traditional pharmacopoeia, where it is valued both as a food and as a versatile nutritional support.
Shiitake stands out for its exceptional richness in bioactive compounds and essential nutrients. It notably contains lentinan, a β-glucan (1-3, 1-6) studied since the 1970s for its immunomodulatory properties, as well as eritadenine, a compound studied for its role in cholesterol balance. Shiitake is also a natural source of ergosterol (a precursor of vitamin D2), B vitamins (B2, B3, B5), copper, selenium and dietary fiber. Several published clinical trials (Gaullier et al., 2011; Dai et al., 2015; Morales et al., 2018) have studied its effects in humans on the immune system and cardiovascular balance.
Our Shiitake Nutrition•pro is a concentrated 10:1 extract of Lentinula edodes in vegetable capsules, the highest extraction ratio in our functional mushroom range. Each bottle contains 60 capsules, a complete 30-day course at 2 capsules per day, providing a daily intake of 1,800 mg of extract. A simple, single-ingredient formula, made in France.
Shiitake is intended for those seeking a versatile nutritional mushroom capable of supporting natural defenses, cardiovascular balance and the intake of essential micronutrients. It easily fits into your daily routine: 2 capsules with a large glass of water, at the time that suits you best.
At Nutrition•pro, we formulate dietary supplements without compromise. Shiitake joins our functional mushroom range alongside Lion's Mane, Reishi, Cordyceps and Chaga: five iconic mushrooms, each with its own identity, to support the different moments of your life.
How to use
Nutritional information
Ingredients per day (2 capsules):
| Ingredients | Composition | NRV % * |
|---|---|---|
| Shiitake extract 10:1 | 1,800 mg | / |
*NRV = Nutrient Reference Values (not established)
Precautions
The nutritional mushroom from the Japanese tradition
Cultivated for over a thousand years in Japan, Shiitake (Lentinula edodes) is the most widely consumed edible mushroom in the world. Its Japanese name means "mushroom (také) of the oak (shii)", referring to the tree on which it naturally grows in Asian forests. A pillar of Japanese, Chinese and Korean cuisine for centuries, it also holds a prominent place in traditional pharmacopoeia, where it is valued both as a food and as a versatile nutritional support.
Shiitake stands out for its exceptional richness in bioactive compounds and essential nutrients. It notably contains lentinan, a β-glucan (1-3, 1-6) studied since the 1970s for its immunomodulatory properties, as well as eritadenine, a compound studied for its role in cholesterol balance. Shiitake is also a natural source of ergosterol (a precursor of vitamin D2), B vitamins (B2, B3, B5), copper, selenium and dietary fiber. Several published clinical trials (Gaullier et al., 2011; Dai et al., 2015; Morales et al., 2018) have studied its effects in humans on the immune system and cardiovascular balance.
Our Shiitake Nutrition•pro is a concentrated 10:1 extract of Lentinula edodes in vegetable capsules, the highest extraction ratio in our functional mushroom range. Each bottle contains 60 capsules, a complete 30-day course at 2 capsules per day, providing a daily intake of 1,800 mg of extract. A simple, single-ingredient formula, made in France.
Shiitake is intended for those seeking a versatile nutritional mushroom capable of supporting natural defenses, cardiovascular balance and the intake of essential micronutrients. It easily fits into your daily routine: 2 capsules with a large glass of water, at the time that suits you best.
At Nutrition•pro, we formulate dietary supplements without compromise. Shiitake joins our functional mushroom range alongside Lion's Mane, Reishi, Cordyceps and Chaga: five iconic mushrooms, each with its own identity, to support the different moments of your life.
Ingredients per day (2 capsules):
| Ingredients | Composition | NRV % * |
|---|---|---|
| Shiitake extract 10:1 | 1,800 mg | / |
*NRV = Nutrient Reference Values (not established)
THE BENEFITS OFSHIITAKE
- Natural antioxidant action
- Rich in vitamins and minerals
- Complete nutritional mushroom
- Supports natural defences
- Supports cardiovascular balance
- Natural source of lentinan and β-glucans
Effectiveness studied in several clinical trials
Shiitake related supplement courses
Frequently asked questions
What is Shiitake and what are its benefits?
Shiitake (Lentinula edodes) is the most widely consumed edible mushroom in the world, cultivated for over a thousand years in Japan. Its name means "mushroom (také) of the oak (shii)" in Japanese, referring to the tree on which it naturally grows in Asian forests.
Beyond its culinary role, Shiitake is studied for its immunomodulatory properties, its role in cardiovascular balance and its nutritional richness. It notably contains lentinan, a (1-3, 1-6) β-glucan studied since the 1970s, as well as eritadenine, studied for its role in cholesterol metabolism.
Our Shiitake food supplement in capsules provides a concentrated 10:1 extract of Lentinula edodes, at 1,800 mg per day, for easy integration into your daily routine.
What is lentinan and what are its effects?
Lentinan is a β-glucan with a (1-3, 1-6) structure extracted from Shiitake. It is one of the most studied bioactive compounds in modern nutritional mycology, with scientific publications since the 1970s.
Lentinan interacts with immune system cells, particularly macrophages, NK cells and T lymphocytes, making it a well-documented natural immunomodulator. Several clinical studies (Gaullier et al., 2011; Dai et al., 2015) have demonstrated its role in supporting natural defences in humans.
In Japan, lentinan has been classified as an immunotherapy medicine since 1985, which testifies to the level of scientific studies accumulated on this compound.
Does Shiitake have an effect on cholesterol?
Shiitake contains a unique bioactive compound called eritadenine (2(R),3(R)-dihydroxy-4-(9-adenyl)-butyric acid), studied for several decades for its role in cholesterol metabolism.
A study published in 2018 (Morales et al.) demonstrated that aqueous Shiitake extracts inhibit HMG-CoA reductase in vitro, the key enzyme in cholesterol metabolism which is also the target of statins. The extracts also inhibit the angiotensin-converting enzyme (ACE), involved in blood pressure regulation.
These in vitro results suggest Shiitake's relevance for supporting cardiovascular balance, alongside a balanced diet and a healthy lifestyle. People taking cholesterol-lowering medication (statins) should seek their doctor's advice before use.
What are Shiitake's bioactive compounds?
Shiitake is a nutritionally very rich mushroom, containing several families of bioactive compounds studied by research:
• Lentinan ((1-3, 1-6) β-glucan): the reference immunomodulatory compound, studied since 1970
• Eritadenine: compound studied for cholesterol metabolism
• Ergosterol: natural precursor of vitamin D2 (ergocalciferol)
• B vitamins (B2, B3, B5): involved in energy metabolism
• Copper and selenium: antioxidant minerals
• Polyphenols and flavonoids: natural antioxidant compounds
• Dietary fibre: promotes digestive balance
This wealth of bioactive compounds makes Shiitake one of the most nutritionally versatile functional mushrooms.
When is the best time to take Shiitake?
Shiitake can be taken at any time of day, according to your rhythm and preference. Its nutritional versatility makes it particularly suitable for intake with a balanced meal, to optimise the absorption of fat-soluble compounds (particularly ergosterol and associated vitamins).
Taking it in the morning or at midday is generally preferred to benefit from its B vitamin content (involved in energy metabolism). Shiitake has no stimulating or sedative effect, making it suitable at any time of day.
A course of at least 30 days is recommended to fully benefit from its properties, as the bioactive compounds (lentinan, eritadenine) act progressively by accumulation.
Why does a 10:1 extract make a difference?
The 10:1 extraction ratio means that 10 kg of raw Shiitake are needed to obtain 1 kg of concentrated extract. It is the highest extraction ratio in our functional mushroom range (the other references are 4:1).
A higher ratio concentrates more of the mushroom's bioactive compounds (lentinan, eritadenine, polysaccharides) in the same quantity of final extract. In concrete terms, 1,800 mg of our 10:1 Shiitake extract is equivalent to 18 g of raw mushroom, i.e. the equivalent of several culinary portions.
This level of concentration delivers a significant quantity of active compounds in just 2 capsules a day, without having to consume large quantities of fresh or dried Shiitake daily.
Can Shiitake be combined with other functional mushrooms?
Yes, Shiitake combines particularly well with the other functional mushrooms in our range, as their properties are complementary.
Relevant combinations: Shiitake + Reishi for complete immune and nervous support; Shiitake + Chaga for reinforced antioxidant action and natural defences; Shiitake + Cordyceps for athletes wishing to combine versatile nutrition and performance; Shiitake + Lion's Mane for those wanting a global body + mind approach.
It is advisable to introduce the mushrooms one at a time over a few days to observe individual tolerance, and to seek advice from a healthcare professional if taking several supplements simultaneously.
Is Shiitake a natural source of vitamin D?
Shiitake is one of the few foods naturally rich in ergosterol, a precursor of vitamin D2 (ergocalciferol). When Shiitake is exposed to UV rays (natural or artificial), ergosterol is converted into vitamin D2.
Our Shiitake food supplement provides a natural source of ergosterol, helping to enrich your diet with vitamin D precursors. However, for a targeted vitamin D intake (particularly in winter or in cases of proven deficiency), direct supplementation with vitamin D3 (cholecalciferol) remains the most effective option, as vitamin D3 is more bioavailable than D2 in humans.
Shiitake nevertheless remains an excellent complement to a balanced diet for naturally supporting the intake of essential micronutrients.
Are there any contraindications to Shiitake?
Shiitake is generally well tolerated in capsule extract form, but certain precautions must be observed.
It is not recommended for pregnant and breastfeeding women, due to insufficient safety data during these periods. Consumption is also not recommended for children and adolescents.
People taking anticoagulant, immunosuppressant or cholesterol-lowering (statin) medication should seek their doctor's advice before use, as Shiitake may interact with these classes of medication. If you are prone to mushroom allergies or have a history of Shiitake dermatitis (a rare skin reaction occurring after consumption of raw or undercooked Shiitake), it is recommended to seek advice from a healthcare professional before use.
For adults only. Do not exceed the recommended daily dose. A food supplement is not a substitute for a varied, balanced diet or a healthy lifestyle.
Is Nutrition•pro Shiitake vegan?
Yes. Our Nutrition•pro Shiitake comes in plant-based capsules (HPMC) and contains no ingredients of animal origin. It is perfectly suitable for vegetarian and vegan diets.
Our formula is also gluten-free, lactose-free, GMO-free, with no added sugar, no colourings and no artificial preservatives. It is therefore suitable for people following specific diets or looking for food supplements with clean compositions.
All products in the Nutrition•pro Functional Mushrooms range are made in France, with particular attention to raw material quality, extract traceability and transparency of compositions.
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