Hydration tablets have become standard in the water bottles of runners, cyclists, and then everyone else over the past few years. Sodium, potassium, magnesium, zero sugar, lemon flavor: the promise is to "hydrate better" than water. On PubMed, the question has been asked for a long time, and the answer is more interesting than the marketing.
Electrolytes are one of the most effective treatments in the history of medicine in a specific context, that of acute diarrhea. They have documented utility in a second context, prolonged exertion in heat. And they do strictly nothing more than water in the third, which is the situation for most people most of the time. This article details all three, and concludes with what these tablets are really worth, including on the point their manufacturers prefer not to address.
Three questions, three answers. In gastroenteritis, oral rehydration solution with sodium and glucose is a reference treatment, validated by a Cochrane review. Duringprolonged exertion in heat, sodium has documented utility: two trials show that a rehydration solution reduces susceptibility to cramps where water alone increases it. In daily life and for a one-hour session, water does the same job.
What really retains water. Of 13 beverages tested in 72 men, the sports drink performed no better than water. Only oral rehydration solution and milk retained more, with a hydration index of approximately 1.5 versus 1.0. The real danger during a race: excess water. 13% of Boston Marathon runners had hyponatremia, and the composition of the beverages made no difference. The tablets: useful for sodium during exertion, of no interest in daily life, and their sugar-free formula lacks the mechanism that makes the reference solution effective.
- What electrolytes are, and what we ask of them
- The case where they save lives
- What really retains water: the beverage index
- During exercise, the danger isn't what you think
- Cramps: what two trials show
- Why your sweat isn't your neighbor's
- Hydration tablets: what they do, what they don't
- Frequently asked questions
What electrolytes are, and what we ask of them
An electrolyte is a mineral that is electrically charged once dissolved in water. The main ones are sodium, potassium, chloride, magnesium, and calcium. They regulate water distribution between blood and cells, nerve signal transmission, and muscle contraction.
For hydration, only one dominates: sodium. It is what retains water in the blood compartment, what is lost in quantity in sweat, and what, when its blood concentration drops, causes hyponatremia. Potassium and magnesium matter for other functions, but their losses through sweat are minimal compared to dietary intake.
"Are electrolytes effective?" has no answer, because it covers three situations that have nothing in common: a gastroenteritis, an ultratrail run in summer, and a office day with a 45-minute workout. In the first, electrolytes are a treatment. In the second, a tool. In the third, a sodium supplement to a diet that already has too much.
The marketing of tablets borrows the legitimacy of the first two to sell in the third. This is the shift that this article will dismantle, situation by situation.
The case where they save lives
We must start there, because that's where all the credibility of the word "electrolytes" comes from. The oral rehydration solution, or ORS, combines in precise proportions sodium, potassium, chloride, a buffer and glucose. As the Cochrane review dedicated to it reminds us, it has reduced infant deaths from diarrhea in many countries.
This review compared the World Health Organization's historical formula to a formula with reduced osmolarity, containing less sodium and less glucose. Out of nine trials, the reduced formula was associated with fewer unscheduled intravenous infusions, with an odds ratio of 0.61, with a lower stool volume and with fewer vomiting episodes, without additional risk of hyponatremia.
Glucose is not there for energy or taste. In the intestine, glucose and sodium are absorbed together by the same transporter, and water follows. It is this coupling that makes a glucose-sodium solution rehydrate faster than salt water alone, and it is the physiological basis of the WHO formula. The Cochrane review explicitly refers to a glucose-based oral rehydration solution.
Remember this point: it will be used to evaluate hydration tablets, whose main selling argument is precisely to contain no sugar.
What really retains water: the beverage index
Here is the most useful study in this file for everyday use. Researchers from Loughborough wanted to measure something simple: after drinking one liter of a given beverage, how much water remains in the body four hours later, compared to one liter of plain water?
72 men each drank one liter of plain water and then, on other visits, one liter of three other beverages among thirteen tested, within thirty minutes. Their urine was collected for four hours. The ratio between water retained after a beverage and water retained after plain water gives thehydration index of that beverage.
| Beverage | 4-hour urine | 2-hour hydration index |
|---|---|---|
| Plain water | 1,337 g | 1.00 by definition |
| Oral rehydration solution | 1,038 g | 1.54 |
| Whole milk | 1,052 g | 1.50 |
| Skim milk | 1,049 g | 1.58 |
| Sports drink | No different from water | Equivalent to water |
| Cola, diet cola, tea, coffee, beer, orange juice, sparkling water | No different from water | Equivalent to water |
Two results deserve to be read carefully.
The first: sports drinks performed no better than water. With its electrolytes, carbohydrates, and marketing, it produced the same amount of urine as tap water. This is not an opinion, it's a measurement across 72 people.
The second: milk, whether whole or skim, retained as much water as oral rehydration solution, the beverage designed by the WHO for this specific purpose. The reason lies in its sodium content, proteins, and energy, which slow gastric emptying and reduce diuresis.
What distinguished the three winning beverages from the other ten was not the presence of electrolytes, it was their amount, and the energy that accompanies them. A typical sports drink contains significantly less sodium than a rehydration solution, which is why it behaves like water. A hydration tablet sits, depending on its formula, somewhere between the two. The question is therefore never "does it contain electrolytes," but "how much sodium, and combined with what".
Honest clarification: this trial was conducted in properly hydrated men at rest. It measures water retention, not athletic performance, and it says nothing about what happens during exertion in heat. For that, other data are needed.
During a race, the danger is not what you think
For decades, the message to runners was to drink before feeling thirsty, as much as possible, at every aid station. Then runners died at the finish of marathons, not from dehydration, but from the opposite.
A study published in the New England Journal of Medicine recruited 766 participants from the 2002 Boston Marathon and analyzed their blood 488 of them at the finish line. 13% had hyponatremia, and 0.6% at a critical level, less than or equal to 120 mmol per liter, a threshold that poses a life-threatening risk.
What was associated with the risk, and what was not
| Factor | Associated with hyponatremia |
|---|---|
| Weight gain during the race | Yes, odds ratio 4.2: the runner drank more than he lost |
| Race time over 4 hours | Yes, odds ratio 7.4 compared to less than 3 h 30 |
| Consumption of more than 3 liters | Yes, in univariate analysis |
| Drinking at every mile | Yes, in univariate analysis |
| Extreme body mass index | Yes |
| Composition of beverages consumed | No |
| Female sex, anti-inflammatory drugs | No, in multivariate analysis |
The composition of beverages was not associated with risk. In other words, runners who drank electrolyte beverages were not better protected than those who drank water. What mattered was the volume. Drinking too much of an electrolyte beverage is still drinking too much.
This is a point that electrolyte tablet marketing carefully avoids, because it inverts the promise: the solution to the problem of exercise-induced hyponatremia is not to add sodium to what you drink, it is to drink less when you are drinking too much.
The international consensus on exercise-induced hyponatremia, convened for the third time in Carlsbad in 2015 and signed by about twenty specialists, including several of the authors cited in this article, drew the following conclusion from this data: the central recommendation is to drink to thirst, rather than to follow a program of predetermined fixed volumes. Electrolytes do not replace this rule. At best, they complement it.
Cramps: what two trials show
This is where electrolytes score points, with reservations that need to be noted. An Australian team conducted two crossover trials on susceptibility to cramping, measured by an objective method: the frequency of electrical stimulation needed to trigger a calf cramp. The lower this threshold frequency, the more easily the muscle cramps.
First trial: drinking after dehydration
Ten men ran downhill at 35 to 36 degrees until they lost 2% of their body weight. Ten minutes later, they drank either spring water or an oral rehydration solution, with the other condition tested a week later.
- Afterwater, the threshold frequency decreased by 4.3 Hz at 30 minutes and by 5.1 Hz at 60 minutes: the muscles cramped more easily than before.
- After the rehydration solution, it increased by 3.7 then 5.4 Hz: the muscles cramped less easily.
- Blood sodium and chloride decreased after water and remained stable after the solution.
Second trial: drinking during exercise
Same team, same protocol, but the drink was consumed during the run, compensating for weight loss measured every ten minutes. Even more clear-cut result: the threshold frequency decreased by 3.8 to 4.5 Hz with water, and increased by 6.5 to 13.6 Hz with the rehydration solution. Blood osmolarity and sodium only decreased in the water condition.
What this tells us: after heavy sweating, drinking only water dilutes the remaining sodium, and this dilution makes the muscle more sensitive to cramping. Replacing sodium at the same time as water reverses this effect. This is consistent, reproducible, and objectively measured.
What this doesn't tell us: these trials involved ten men each, under extreme conditions, with a cramp electrically induced and not occurring spontaneously during competition. The tested drink was an oral rehydration solution, rich in sodium and containing glucose, not a sports tablet. Finally, exercise-related cramping has other recognized causes, notably neuromuscular fatigue, which electrolytes do not address.
Why your sweat is not your neighbor's
A tablet delivers a fixed dose of sodium. Yet the reference journal on the subject, published in Sports Medicine, establishes that sweat rate and its sodium concentration vary considerably from one person to another, and in the same person depending on intensity, heat, acclimatization, fitness level, body size, sex, age, and diet.
This same journal examines the sweat tests used to personalize intake, and concludes that non-standardized methods and field conditions often produce inconsistent or inaccurateresults. The only simple and reliable benchmark is the change in body weight during exercise, which reflects water loss.
This journal is authored by a researcher from the Gatorade Sports Science Institute, a subsidiary of PepsiCo. We cite it because its methodology is sound and its conclusions cautious, but it is fair that you know this. A beverage manufacturer has an interest in sodium being taken seriously. This does not invalidate individual variability, which is a well-established fact; it invites you to read the practical recommendations that follow with appropriate caution.
What is important to remember is almost paradoxical: individual variability is the strongest argument for attention to sodium in heavy sweaters, and the strongest argument against the idea that a standard tablet could suit everyone.
Hydration tablets: what they do, what they don't do
An effervescent hydration tablet most often contains a few hundred milligrams of sodium, potassium, sometimes magnesium and calcium, flavoring, a sweetener, and little or no sugar. Let's compare this to the data.
| Situation | What the data says | Is the tablet useful? |
|---|---|---|
| Gastroenteritis | Sodium and glucose ORS is the standard treatment | No : wrong tool, use a pharmacy ORS |
| Prolonged exercise in heat, heavy sweating | Sodium reduces susceptibility to cramps that water alone increases | Yes, for sodium intake, provided you drink according to thirst |
| Marathon, hyponatremia prevention | The composition of beverages was not associated with risk, volume was | No as protection: not drinking too much is the only remedy |
| One-hour session, normal conditions | Sports drink retains no more water than water | No : water is sufficient |
| Daily use outside exercise | No supporting evidence; diet already provides too much sodium | No, and to monitor in case of hypertension |
| Hangover | No identified trial showing an advantage over water | Not demonstrated |
The point manufacturers don't address
Oral rehydration solution works because it combines sodium with glucose, absorbed together by the intestine, water following suit. It is this coupling, not simply the presence of sodium, that makes the WHO formula effective. The two trials on cramps used a solution of this type, with glucose.
A tablet formulated without sugar provides sodium, but lacks the mechanism that accelerates its absorption. It is not useless nonetheless: the sodium will eventually be absorbed. But it is further removed from the reference formula than the word "electrolytes" on the label and the "zero sugar" presented as an advantage would suggest, and physiologically speaking, "zero sugar" is a compromise.
What a tablet does well
To be fair: in its context, a tablet provides a real service. It delivers sodium in a practical, measured and portable form, which matters on a bike or trail run. It provides a taste that encourages some people to drink more when they need to. And it avoids the pitfall documented by cramp trials—that of compensating for heavy sweating with water alone.
The problem is not the product. It's the usage drift : a tool designed for ultra-endurance in heat, sold as a daily wellness gesture to people whose only exertion is climbing metro stairs. For them, the tablet adds sodium to a diet already containing too much.
What to do practically
Nausea, vomiting, headaches, confusion, swelling of hands and feet, and in severe cases convulsions or altered consciousness, in someone who drank heavily during a long effort. These signs resemble those of dehydration, which sometimes leads those around them to make the person drink more and worsen the situation. Faced with this picture after a long race, it is a medical emergency.
Frequently asked questions
The fundamental question
Are electrolytes really effective?
The question has no single answer, because it covers three unrelated situations. In acute diarrhea, the oral rehydration solution with sodium and glucose is a reference treatment that has reduced childhood mortality in many countries. In prolonged effort in heat, sodium has documented utility on certain criteria. In daily life or for a one-hour session, water does exactly the same job, and a sports drink does not surpass it.
What is an electrolyte, concretely?
A mineral that carries an electrical charge once dissolved in water: sodium, potassium, chloride, magnesium, calcium. They regulate the distribution of water between body compartments, nerve transmission, and muscle contraction. Sodium is by far the most important for hydration, because it is what retains water in the blood and what is lost in quantity in sweat.
What should you remember about electrolytes?
That they are a treatment for diarrhea, in the form of an oral rehydration solution with sodium and glucose. That in prolonged effort in heat, sodium has documented utility, particularly on susceptibility to cramps, but that the first rule is to drink to your thirst because excess water is the real danger. That for an ordinary session, water is sufficient and a sports drink does not do better. And that sugar-free tablets provide sodium while forgoing the mechanism that makes the reference formula effective.
Hydration and beverages
Does a sports drink hydrate better than water?
No, and it's measurable. In the trial that established the hydration index of beverages, 72 men drank one liter each of 13 different beverages, then their urine production was monitored for four hours. The sports drink did not retain more water than plain water. The only beverages that did better were oral rehydration solution, whole milk, and skim milk, with an index of approximately 1.5 versus 1.0 for water.
Why do milk and oral rehydration solution retain water better?
Because they provide significant amounts of sodium and nutrients that slow gastric emptying and reduce diuresis. A classic sports drink contains significantly less sodium than a rehydration solution, which explains why it behaves like water in this trial. The lesson is simple: it's not the presence of electrolytes that matters, it's their dose.
Do you need electrolytes for an ordinary sports session?
For a session of about one hour, under normal conditions, water is sufficient and sodium losses are largely compensated by food intake during the rest of the day. The question of electrolytes becomes relevant for prolonged efforts, in heat, in people who sweat heavily, or when multiple sessions occur in succession during the day.
Should you drink on a schedule or according to thirst?
According to thirst, for the majority of practitioners. This is the recommendation of the international consensus on exercise-associated hyponatremia, motivated by the fact that severe cases almost always occur in people who drank beyond their losses by following volume guidelines. Rare exceptions concern very specific contexts supervised by professionals.
Exercise, hyponatremia and cramps
What is the real danger during a marathon: dehydration or excess water?
Excess water kills more surely than dehydration. In a Boston Marathon cohort, 13% of the 488 runners analyzed at the finish line had hyponatremia, and 0.6% at a critical level. The main associated factor was weight gain during the race, that is, drinking more than was lost. Consuming more than three liters and drinking at every mile were among the associated behaviors.
Does an electrolyte drink protect against hyponatremia?
Not in the available data. In the Boston study, the composition of beverages consumed was not associated with the risk of hyponatremia, unlike the quantity. In other words, drinking too much of an electrolyte drink is still drinking too much. The international consensus on exercise-associated hyponatremia recommends drinking according to thirst rather than following a fixed schedule. Electrolytes do not replace this rule; at best, they complement it.
What are the signs of exercise-associated hyponatremia?
Nausea, vomiting, headache, confusion, swelling of hands and feet, and in severe cases convulsions or loss of consciousness, in someone who drank heavily during prolonged exercise. These signs resemble those of dehydration, which sometimes leads to drinking more and worsening the situation. Faced with this presentation after a long race, it is a medical emergency.
Do electrolytes prevent cramps?
Two crossover trials provide a clear signal, in small numbers. In ten men dehydrated by 2% through downhill running at 35 degrees, drinking spring water made muscles more susceptible to electrically-induced cramps, while an oral rehydration solution had the opposite effect. The same result was found when the beverage was consumed during exercise. Blood sodium and chloride decreased with water alone and were maintained with the solution.
Can water therefore worsen cramps?
In a specific context, yes: after significant dehydration from sweating, drinking only water dilutes remaining sodium, and this dilution appears to increase susceptibility to cramps in these trials. This is not an argument against water in general; it is an argument for also replacing sodium when you have sweated heavily.
How much sodium is lost through sweating?
This varies enormously from one person to another and, in the same person, depending on intensity, heat, acclimatization and training. This is the central conclusion of the reference review on the subject: there is no universal figure, and replacement recommendations must be individualized. Two people doing the same session can lose very different amounts of sodium.
Can you determine your own sodium loss?
Sweat tests exist, but the review examining them emphasizes that non-standardized methods and field conditions often produce inconsistent results. A more accessible benchmark is weight loss during exercise, which reflects water loss. For sodium, white stains on clothing and eye irritation are crude indicators of salty sweat, without measurement value.
Hydration tablets
What do hydration tablets contain?
Most often, a few hundred milligrams of sodium per tablet, potassium, sometimes magnesium and calcium, a flavoring and a sweetener, with little or no sugar. This last point deserves attention: it is both their sales argument and what distances them from the formula whose effectiveness is best demonstrated.
Why is the absence of sugar a problem?
Because the reference oral rehydration solution combines sodium with glucose, and this combination is not decorative: glucose and sodium are absorbed together by the intestine, and glucose accelerates the absorption of sodium and water. This is the physiological basis of the solution recommended by the World Health Organization. A tablet without sugar provides sodium, but deprives itself of the mechanism that makes the original formula effective.
Is a hydration tablet therefore useless?
No, it has a specific use: providing sodium during prolonged exercise or in high heat, when you sweat heavily and drink heavily. In this context, replacing sodium rather than drinking only water makes sense, as shown by cramp trials. Outside this context, in an ordinary day, it adds sodium to a diet that already generally contains too much.
Should you take electrolytes every day?
Nothing supports this for a healthy person eating normally. Common diet provides sodium in excess rather than deficiency, and potassium comes from fruits and vegetables. A daily tablet outside of exercise therefore mainly adds sodium where it is not lacking. People with high blood pressure or under treatment should be particularly careful about this additional intake.
Do electrolytes help with hangovers?
We did not identify any trial demonstrating that an electrolyte tablet reduces hangover symptoms. Alcohol has a diuretic effect and rehydration is reasonable, but nothing shows that an electrolyte drink performs better than water in this context. Marketing use on this ground goes beyond the data.
What should you do in case of gastroenteritis?
This is the only context where electrolytes are part of treatment, and you should use a pharmaceutical oral rehydration solution, not a sports tablet. A Cochrane review of hospitalized children with diarrhea shows that the reduced osmolarity formula reduces the need for intravenous therapy, stool volume and vomiting compared to the standard formula. In infants, elderly people or in case of signs of dehydration, consult a healthcare provider.
Glossary
- Electrolyte
- A mineral carrying an electrical charge once dissolved: sodium, potassium, chloride, magnesium, calcium.
- Oral rehydration solution (ORS)
- A formula combining sodium, potassium, chloride, buffer and glucose in defined proportions, the reference treatment for dehydration from diarrhea.
- Osmolarity
- Total concentration of dissolved particles in a liquid, which determines its water movements with the body.
- Hydration index of beverages
- Water retained two hours after drinking a beverage, compared to that retained after one liter of plain water.
- Hyponatremia
- Reduced blood sodium concentration, at 135 mmol per liter or less, potentially fatal below 120.
- Exercise-associated hyponatremia
- Hyponatremia occurring during or after prolonged exercise, most often due to fluid consumption exceeding losses.
- Cramp threshold frequency
- Frequency of electrical stimulation required to trigger a cramp; the lower it is, the more susceptible the muscle is.
- Glucose-sodium cotransport
- Intestinal mechanism by which glucose and sodium are absorbed together, drawing in water, the basis of oral rehydration formula.
- Drinking to thirst
- Strategy recommended by the exercise-associated hyponatremia consensus, as opposed to a program of fixed volumes planned in advance.
Sources
The studies cited below were identified via PubMed.
- Maughan RJ, et al. Randomized trial evaluating the potential of different beverages to modify hydration status: development of a beverage hydration index. American Journal of Clinical Nutrition, 2016;103(3):717-723. DOI
- Almond CS, et al. Hyponatremia among runners of the Boston Marathon. New England Journal of Medicine, 2005;352(15):1550-1556. DOI
- Hew-Butler T, et al. Statement from the third international conference of consensus on hyponatremia associated with exercise, Carlsbad, 2015. Clinical Journal of Sport Medicine, 2015;25(4):303-320. DOI
- Lau WY, Kato H, Nosaka K. Water intake after dehydration makes muscles more susceptible to cramping, but electrolytes reverse this effect. BMJ Open Sport & Exercise Medicine, 2019;5(1):e000478. DOI
- Lau WY, Kato H, Nosaka K. Effect of an oral rehydration solution versus spring water during exercise in the heat on cramp susceptibility in young men. Journal of the International Society of Sports Nutrition, 2021;18(1):22. DOI
- Baker LB. Sweat rate and sweat sodium concentration in athletes: a review of methodology and intra- and inter-individual variability. Sports Medicine, 2017;47(Suppl 1):111-128. Author affiliated with the Gatorade Sports Science Institute. DOI
- Hahn S, Kim Y, Garner P. Low osmolarity oral rehydration solution for treating dehydration caused by acute diarrhea in children. Cochrane Database of Systematic Reviews, 2002;(2):CD002847. DOI


